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We have designed GenomeBrowse to scale wonderfully to whole genome DNA-seq data, and there are no hard-coded limits on file size or read density or pretty much anything.

What generally becomes the constrained resource in any big-data visualization system is how much data you can hold in RAM to render your plots in full detail.

Even here we have worked to make the worst-case scenario of millions and millions of reads in a small (<10kb) window at least not break GenomeBrowse. Instead, we drop some reads from the pile-up plot but continuing to count them in the coverage plot. You will get a little warning icon on the bottom of your pile-up plot if you do ever get to such a high-density region.

If you experience any failures to handle large files, we would consider it a bug. In such cases we ask for your help if at all possible to share your data security so we can reproduce and resolve the issue.

We have designed GenomeBrowse to scale wonderfully to whole genome DNA-seq data, and there are no hard-coded limits on file size or read density or pretty much anything.

What generally becomes the constrained resource in any big-data visualization system is how much data you can hold in RAM to render your plots in full detail.

Even here we have worked to make the worst-case scenario of millions and millions of reads in a small (<10kb) window at least not break GenomeBrowse. Instead, we drop some reads from the pile-up plot but while continuing to count them in the coverage plot. You will get a little warning icon on the bottom of your pile-up plot if you do ever get to such a high-density region.

If you experience any failures to handle large files, we would consider it a bug. In such cases we ask for your help if at all possible to share your data security securely so we can reproduce and resolve the issue.